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spindle pole body separation definition: A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble. [GOC:sgd_curators]
regulation of spindle pole body separation definition: Any process that modulates the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339]
positive regulation of spindle pole body separation definition: Any process that increases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339]
negative regulation of spindle pole body separation definition: Any process that decreases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. [GOC:dph, GOC:tb, PMID:16792804, PMID:18500339]