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Translation
 
enEnglish frFrench
2 words
sigma subunit facteur sigma
 
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enEnglish deGerman
1 word
subunit Untereinheit
 
Definition
 
enEnglish
alpha-Crystallin A Chain definition: One of the subunits of alpha-crystallins. Unlike ALPHA-CRYSTALLIN B CHAIN the expression of ALPHA-CRYSTALLIN A CHAIN is limited primarily to the lens (LENS, CRYSTALLINE).
Glycoprotein Hormones, alpha Subunit definition: The alpha chain of pituitary glycoprotein hormones (THYROTROPIN; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE) and the placental CHORIONIC GONADOTROPIN. Within a species, the alpha subunits of these four hormones are identical; the distinct functional characteristics of these glycoprotein hormones are determined by the unique beta subunits. Both subunits, the non-covalently bound heterodimers, are required for full biologic activity.
Sigma Factor definition: A protein which is a subunit of RNA polymerase. It effects initiation of specific RNA chains from DNA.
Follicle Stimulating Hormone, beta Subunit definition: The beta subunit of follicle stimulating hormone. It is a 15-kDa glycopolypeptide. Full biological activity of FSH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the FSHB gene causes delayed puberty, or infertility.
Luteinizing Hormone, beta Subunit definition: The beta subunit of luteinizing hormone. It is a 15-kDa glycopolypeptide with structure similar to the beta subunit of the placental chorionic gonadatropin (CHORIONIC GONADOTROPIN, BETA SUBUNIT, HUMAN) except for the additional 31 amino acids at the C-terminal of CG-beta. Full biological activity of LH requires the non-covalently bound heterodimers of an alpha and a beta subunit. Mutation of the LHB gene causes HYPOGONADISM and infertility.
Thyrotropin, beta Subunit definition: The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH requires the non-covalently bound heterodimers of an alpha and a beta subunit.
Integrin alpha1 definition: An integrin alpha subunit that binds COLLAGEN and LAMININ though its I domain. It combines with INTEGRIN BETA1 to form the heterodimer INTEGRIN ALPHA1BETA1.
alpha-Crystallin B Chain definition: One of the alpha crystallin subunits. In addition to being expressed in the lens (LENS, CRYSTALLINE), alpha-crystallin B chain has been found in a variety of tissues such as HEART; BRAIN; MUSCLE; and KIDNEY. Accumulation of the protein in the brain is associated with NEURODEGENERATIVE DISEASES such as CREUTZFELDT-JAKOB SYNDROME and ALEXANDER DISEASE.
Inhibin Beta A definition: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. (from LocusLink)
Protein Subunits definition: Single chains of amino acids that are the units of multimeric PROTEINS. Multimeric proteins can be composed of identical or non-identical subunits. One or more monomeric subunits may compose a protomer which itself is a subunit structure of a larger assembly.
22 further definitions >>
Publications
 

Internal structure of the chromatin subunit

Markus Noll

Nucleic Acids Research , 01 Nov 1974

The HsdR subunit of R.EcoR124II: cloning and over-expression of the gene and unexpected properties of the subunit.

V Zinkevich et al.

Nucleic Acids Research , 01 Feb 1997

Involvement of multiple subunit–subunit contacts in the assembly of RNA polymerase II

Makoto Kimura et al.

Nucleic Acids Research , 15 Feb 2000

The Small Subunit rRNA Modification Database

James A. McCloskey et al.

Nucleic Acids Research , 01 Jan 2005

A novel GTPase activated by the small subunit of ribosome

Hyouta Himeno et al.

Nucleic Acids Research , 2004

Database on the structure of large ribosomal subunit RNA.

P De Rijk et al.

Nucleic Acids Research , 01 Sep 1994

The C-terminal zinc finger of the catalytic subunit of DNA polymerase δ is responsible for direct interaction with the B-subunit

Javier Sanchez Garcia et al.

Nucleic Acids Research , 2004

The European Large Subunit Ribosomal RNA Database

Jan Wuyts et al.

Nucleic Acids Research , 01 Jan 2001

Expression of pGKL killer 28K subunit in Saccharomyces cerevisiae: identification of 28K subunit as a killer protein.

M Tokunaga et al.

Nucleic Acids Research , 11 May 1989

Crystal Structure of the P Pilus Rod Subunit PapA

Denis Verger et al.

PLoS Pathogens , 01 May 2007

2202 further publications >>