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Tel: +44 141 330 4628; Fax: +44 141 330 4620; Email: rwhite@udcf.gla.ac.uk Correspondence may also be addressed to M.R.P: Tel: +1 970 491 6748; Fax: +1 970 491 0494; Email: mpaule@lamar.colostate.edu 15 3 2000 28 6 1283 1298 24 11 1999 21 1 2000 21 1 2000 Copyright © 2000 Oxford University Press 2000 The task of transcribing nuclear genes is shared between three RNA polymerases in eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA and pol III synthesises tRNA and 5S rRNA.

Marvin R. Paule et al.

Nucleic Acids Research 28 (6), 15 Mar 2000

Pol I synthesises rRNA and pol III makes 5S rRNA, tRNA, 7SL RNA, U6 snRNA and a few other small stable RNAs, many involved in RNA processing.

Marvin R. Paule et al.

Nucleic Acids Research 28 (6), 15 Mar 2000

Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalization.

Saied Hosseini-Asl et al.

International Seminars in Surgical Oncology 3 (7), 22 Aug 2006

Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalisation. hTERT (human telomerase reverse transcriptase) is the rate-limiting determinant of telomerase reactivation.

Katharine L Kirkpatrick et al.

Journal of Carcinogenesis 3 (7), 22 Jan 2004

Epithelium synthesises nitric oxide (NO) which may be important in regulating the function of airways smooth muscles.

K Gourgoulianis et al.

Mediators of Inflammation 7 (6), 1998

3 further examples >>
Publications
 

Transcription by RNA polymerases I and III: ... RNA polymerase (pol) I synthesises the large rRNA, pol II ...

Marvin R. Paule et al.

Nucleic Acids Research , 15 Mar 2000

The expression of hTR and hTERT in human breast cancer: correlation with clinico-pathological parameters: ... enzyme that synthesises telomeres after cell ...

Saied Hosseini-Asl et al.

International Seminars in Surgical Oncology , 22 Aug 2006

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression: ... enzyme that synthesises telomeres after cell ...

Katharine L Kirkpatrick et al.

Journal of Carcinogenesis , 22 Jan 2004

Epithelium-dependent regulation of airways smooth muscle function. A histamine-nitric oxide pathway.: ... factors. Epithelium synthesises nitric oxide (NO) which ...

K Gourgoulianis et al.

Mediators of Inflammation , 1998

Analysis of the structure of human telomerase RNA in vivo: ... transcriptase that synthesises telomeric DNA. The RNA ...

Mária Antal et al.

Nucleic Acids Research , 15 Feb 2002

Bivariate random-effects meta-analysis and the estimation of between-study correlation: ... separate univariate synthesises; this paper highlights ...

Richard D Riley et al.

BMC Medical Research Methodology , 12 Jan 2007

There is no correlation between c-Myc mRNA expression and telomerase activity in human breast cancer: ... enzyme that synthesises telomeres after cell ...

Katharine L Kirkpatrick et al.

International seminars in surgical oncology : ISSO , 06 May 2004

hTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancer: ... enzyme that synthesises telomeres after cell ...

AE Elkak et al.

Journal of Carcinogenesis , 04 Oct 2005