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Traditional medicinal plant use in Northern Peru: tracking two thousand years of healing culture

Rainer W Bussmann et al.

Journal of Ethnobiology and Ethnomedicine , 07 Nov 2006

Polymorphisms in the selenoprotein S gene: lack of association with autoimmune inflammatory diseases: ... genotyped in more than two thousand patients suffering from ...

Alfonso Martínez et al.

BMC Genomics , 14 Jul 2008

A set of viral DNA decamers enriched in transcription control signals.: ... control signals. Two thousand three hundred decamers ...

S Volinia et al.

Nucleic Acids Research , 11 Jul 1991

Selective single blastocyst transfer reduces the multiple pregnancy rate and increases pregnancy rates: a pre- and postintervention study: ... Population Two thousand four hundred and ...

Y Khalaf et al.

Bjog , 01 Feb 2008

Evolutionary, structural and functional relationships revealed by comparative analysis of syntenic genes in Rhizobiales: ... species-specific. About two thousand genes were predicted to ...

Gabriela Guerrero et al.

BMC Evolutionary Biology , 17 Oct 2005

An assessment of population structure in eight breeds of cattle using a whole genome SNP panel: ... taurus . Results Two thousand six hundred and forty ...

Stephanie D McKay et al.

BMC Genetics , 20 May 2008

A qualitative study of a psychiatric emergency: ... Methods Over twenty-two thousand PES visits were ...

Yves Chaput et al.

International Journal of Mental Health Systems , 30 Jun 2008

Gynaecological morbidity among HIV positive pregnant women in Cameroon: ... women. Methods Two thousand and eight (2008) ...

Enow R Mbu et al.

Reproductive Health , 03 Jul 2008

Successful colonoscopy; completion rates and reasons for incompletion.: ... competence. Details of two thousand two hundred and sixteen ...

R. M. S. Mitchell et al.

The Ulster Medical Journal , 01 May 2002

Ornithine decarboxylase antizyme finder (OAF): Fast and reliable detection of antizymes with frameshifts in mRNAs: ... are encoded by two partially overlapping open reading frames (ORFs). A +1 frameshift between frames is required for the synthesis of antizyme. Ribosomes change translation phase at the end of the first ORF in response to stimulatory signals embedded in mRNA. Since standard sequence analysis pipelines are currently unable to recognise sites of programmed ribosomal frameshifting, proper detection of full length antizyme coding sequences (CDS) requires conscientious manual evaluation by a human expert. The rapid growth of sequence information demands less laborious and more cost efficient solutions for this problem. This manuscript describes a rapid and accurate computer tool for antizyme CDS detection that requires minimal human involvement. Results We have developed a computer tool, OAF ( O DC a ntizyme f inder) for identifying antizyme encoding sequences in spliced or intronless nucleic acid sequenes. OAF utilizes a combination of profile hidden Markov models (HMM) built separately for the products of each open reading frame constituting the entire antizyme coding sequence. Profile HMMs are based on a set of 218 manually assembled antizyme sequences. To distinguish between antizyme paralogs and orthologs from major phyla, antizyme sequences were clustered into twelve groups and specific combinations of profile HMMs were designed for each group. OAF has been tested on the current version of dbEST, where it identified over six thousand Expressed Sequence Tags ...

Michaël Bekaert et al.

BMC Bioinformatics , 02 Apr 2008

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