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Translation
 
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1 word
Tyrosine Tyrosin
 
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Definition
 
enEnglish
Diiodotyrosine definition: A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).
Dihydroxyphenylalanine definition: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
dihydroxyphenylalanine definition: D1 and D2 agonist; precursor in dopamine biosynthesis; levodopa or L-DOPA is the generic name of the antiparkinson drug.
Iodide Peroxidase definition: A hemeprotein that catalyzes the oxidation of the iodide radical to iodine with the subsequent iodination of many organic compounds, particularly proteins. EC 1.11.1.8.
Thyroid Peroxidase definition: Human thyroid peroxidase protein (933 aa, ~103 kDa isoform) is encoded by the human thyroid peroxidase (TPO) gene. This protein is the primary enzyme involved in thyroid hormone synthesis.
Levodopa definition: The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
levodopa definition: naturally occuring form of DOPA and precursor of dopamine; used as an antiparkinsonian agent; unlike dopamine it can be administered orally.
levodopa definition: An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinson's disease. To assure that adequate concentrations of levodopa reach the central nervous system, it is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, thereby diminishing the decarboxylation and inactivation of levodopa in peripheral tissues and increasing the delivery of dopamine to the CNS. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42622&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42622&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C611" NCI Thesaurus)
Levodopa definition: An amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brain, levodopa is decarboxylated to dopamine and stimulates the dopaminergic receptors, thereby compensating for the depleted supply of endogenous dopamine seen in Parkinson's disease. To assure that adequate concentrations of levodopa reach the central nervous system, it is administered with carbidopa, a decarboxylase inhibitor that does not cross the blood-brain barrier, thereby diminishing the decarboxylation and inactivation of levodopa in peripheral tissues and increasing the delivery of dopamine to the CNS.
Neuropeptide Y definition: A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.
26 further definitions >>
frFrench
tyrosine definition: Produit de l’action de la potasse sur la caséine, sur la fibrine ou l’albumine sèche.
 
Publications
 

Deranged Tyrosine Metabolism in Cirrhosis

J. Timothy Fulenwider et al.

The Yale Journal of Biology and Medicine , 1978

Photosensitized formation of thymine dimers in DNA by tyramine, tyrosine and tyrosine-containing peptides.

M Kaneko et al.

Nucleic Acids Research , 01 Mar 1979

Tyrosine kinase – Role and significance in Cancer

Manash K. Paul et al.

International Journal of Medical Sciences , 01 Jun 2004

Tyrosine Sulfation of Statherin

C. Kasinathan et al.

International Journal of Biological Sciences , 02 Mar 2007

RTKdb: database of receptor tyrosine kinase

Julien Grassot et al.

Nucleic Acids Research , 01 Jan 2003

Tyrosine kinase signalling in breast cancer

Nancy E Hynes

Breast Cancer Research , 2000

Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases

David F Stern

Breast Cancer Research , 2000

Implications of tyrosine phosphoproteomics in cervical carcinogenesis

Bernice L Robinson-Bennett et al.

Journal of Carcinogenesis , 17 Jul 2008

Structural Basis for the Regulation Mechanism of the Tyrosine Kinase CapB from Staphylococcus aureus

Vanesa Olivares-Illana et al.

PLoS Biology , 01 Jun 2008

Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

Rajesh K Naz et al.

Reproductive biology and endocrinology : RB&E , 09 Nov 2004

849 further publications >>