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yttrium Y90 ibritumomab tiuxetan definition: An anticancer drug that is a combination of a monoclonal antibody and a radioisotope (yttrium-90). Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells. Also called IDEC-Y2B8 monoclonal antibody.
Yttrium Y 90 Ibritumomab Tiuxetan definition: A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation.
yttrium Y 90 ibritumomab tiuxetan definition: A radioimmunotherapeutic agent consisting of a murine monoclonal anti-CD20 antibody (ibritumomab) linked by the chelator tiuxetan to the radioisotope yttrium-90 (Y 90). Yttrium Y 90 ibritumomab tiuxetan binds to and specifically delivers beta radiation to CD20-expressing tumor cells, thereby minimizing the systemic effects of radiation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38483&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38483&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1812" NCI Thesaurus)
 
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